Errata - English

In USP Metoprolol Related Compound C RS: Change
(±)4-[2-Hydroxy-3-(1-methylethyl)aminopropoxy]benzaldehyde.
C₁₃H₁₉NO₃ 237.29
to:
4-[2-Hydroxy-3-(isopropylamino)propoxy]benzaldehyde hydrochloride.
C₁₃H₁₉NO₃ · HCl 273.76
AND
In USP Metoprolol Related Compound D RS: Change
(±) N,N-Bis[2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl](1-methylethyl)amine.
C₂₇H₄₁NO₆ 475.62
to:
N,N-Bis{2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl}isopropylamine hydrochloride; also known as (±) N,N-Bis[2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl](1-methylethyl)amine hydrochloride.
C₂₇H₄₁NO₆ · HCl 512.08

Change
Diluent 1—Prepare a solution of 0.1 mL of phosphoric acid in 1000 mL of water.
Diluent 2—Prepare a mixture of Diluent 1 and acetonitrile (60:40).
to:
Diluent 1—Prepare a solution of 0.1 mL of phosphoric acid in 1000 mL of water.

In System suitability/Suitability requirements/Peak-to-valley ratio: Change
NLT 1.5 for loperamide related compounds G and H; NLT 1.5 for loperamide related compounds E and A, System suitability solution
to:
NLT 1.5 for loperamide cis-N-oxide and anhydroloperamide; NLT 1.5 for loperamide piperidinolamide and loperamide biphenyl analog, System suitability solution

In Table 3: Delete
Propofol related compound B^b 0.8 1.0 0.05
AND
Change
Propofol related compound A^c
to:
Propofol related compound A^b
AND
Change
^b2,6-Diisopropylbenzoquinone.
^c3,3′-5,5′-Tetraisopropyldiphenol.
to:
^b3,3′-5,5′-Tetraisopropyldiphenol.

In Bicarbonate/B.: Change
(1:20)
to:
(1 in 20)
AND
In Borate/A.: Change
(1:50):
to:
(1 in 50):
AND
In Calcium/A.: Change
(1:20)
to:
(1 in 20)
AND
In Carbonate/B.: Change
(1:20)
to:
(1 in 20)
AND
In Chloride/B.: Change
(1:100),
to:
(1 in 100),
AND
In Cobalt/A.: Change
(1:20)
to:
(1 in 20)
AND
Change
(1:10)
to:
(1 in 10)
AND
In Tartrate/A.: Change
(1:20).
to:
(1 in 20).

In Standard solution 3: Change
USP Methyl Caproate RS, USP Methyl Caprylate RS, USP Methyl Caprate RS, USP Methyl Laurate RS, and USP Methyl Laurate RS.
to:
USP Methyl Caproate RS, USP Methyl Caprylate RS, USP Methyl Caprate RS, USP Methyl Laurate RS, and USP Methyl Myristate RS.

In Biotin, Method 3/Solid-phase extraction: Change
anion-xchange
to:
anion-exchange
AND
In the Calculate statement in Niacin or Niacinamide, Pyridoxine Hydrochloride, Riboflavin, and Thiamine, Method 1/Analysis: Delete
, calcium pantothenate (C₁₈H₃₂CaN₂O₁₀), and folic acid (C₁₉H₁₉N₇O₆),
AND
In the Calculate statement in Niacin or Niacinamide, Pyridoxine Hydrochloride, Riboflavin, and Thiamine, Method 3/Analysis: Delete
, calcium pantothenate (C₁₈H₃₂CaN₂O₁₀), and folic acid (C₁₉H₁₉N₇O₆),
AND
In the Calculate statement in Folic Acid, Method 3; Ascorbic Acid, Niacin or Niacinamide, Pyridoxine Hydrochloride, Calcium Pantothenate, Riboflavin, and Thiamine, Method 4/Analysis: Add
ascorbic acid (C₆H₈O₆),

In the Calculate statement in Niacin or Niacinamide, Pyridoxine Hydrochloride, Riboflavin, and Thiamine, Method 1/Analysis: Delete
, calcium pantothenate (C₁₈H₃₂CaN₂O₁₀), and folic acid (C₁₉H₁₉N₇O₆),
AND
In the Calculate statement in Niacin or Niacinamide, Pyridoxine Hydrochloride, Riboflavin, and Thiamine, Method 3/Analysis: Delete
, calcium pantothenate (C₁₈H₃₂CaN₂O₁₀), and folic acid (C₁₉H₁₉N₇O₆),
AND
In the Calculate statement in Folic Acid, Method 3; Ascorbic Acid, Niacin or Niacinamide, Pyridoxine Hydrochloride, Calcium Pantothenate, Riboflavin, and Thiamine, Method 4/Analysis: Add
ascorbic acid (C₆H₈O₆),